Chemical Formula. Derivative Classification Training The purpose of this job aid is to provide quick reference information for the responsibilities and procedures associated with derivative classification. Theophylline competitively blocks phosphodiesterase which increases cAMP tissue concentrations causing bronchodilatation, diuresis, CNS and cardiac stimulation, and gastric acid secretion. The xanthine derivatives are agents that resemble natural occurring xanthines such as caffeine, theobromine and methylxanthines. Indications C5-H4-N4-O2. Anticholingeric Agent. Therapeutic Categories. These are plant alkaloids and components of coffee, tea and chocolate. Xanthine DerivativesXanthine derivatives such as theophylline inhibit phosphodiesterase, resulting in an increase in cAMP. This job aid also provides an overview of the approved security classification documents that assist in analyzing and evaluating … Bronchial dilation and increase focus of contraction of diaphragmatic muscle. Xanthine Derivatives. Xanthine CAS registry number (Chemical Abstracts Service) 0000069-89-6. 48:12.12 Xanthine Derivatives* 48:16 Expectorants 48:24 Mucolytic Agents* 48:36 Pulmonary Surfactants 48:48 Vasodilating Agents* 48:92 Respiratory Agents, Miscellaneous 52:00 Eye, Ear, Nose, and Throat (EENT) Preparations 52:02 Antiallergic Agents 52:04 Anti-infectives 52:04.04 Antibacterials 52:04.16 … resulting from hydroxylation of Xanthine derivatives (uric acid derivatives) or demethylation products showed to be able to repair radicals resulting from adenine oxidation [12]. Clinical significance. In the case of antipyrine derivatives demethylation reactions from the amino group induced by the hydroxyl radical were also … These medications open the airways, but they work on different receptors in the body. Pregnancy Category C Therapeutic actions. Decrease inflammation. The increase in cAMP causes relaxation of bronchial smooth muscle. In contrast to other, more potent stimulants like sympathomimetic amines, xanthines … Two xanthine derivatives with high affinity and high selectivity for adenosine A 1 receptor, 8-cyclopentyl-1,3-dipropylxanthine (DPCPX) (Lohse et al., 1987) and its analog 8-dicyclopropylmethyl-1,3-dipropylxanthine (KF15372) (Shimada et al., 1991), were selected as lead compounds for in vivo imaging. Theophylline, also known as 1,3-dimethylxanthine, is a phosphodiesterase inhibiting drug used in therapy for respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma under a variety of brand names. The major pharmacologic actions of the xanthines are inhibition of tissue phosphodiesterases which i … As a member of the xanthine family, it bears structural and pharmacological similarity to theobromine … ... Ipratropium Bromide classification. Inhalation and Intranasal spray. Mast Cell Stabilizers. Derivatives of xanthine (known collectively as xanthines) are a group of alkaloids commonly used for their effects as mild stimulants and as bronchodilators, notably in the treatment of asthma or influenza symptoms. Theophylline relaxes bronchial smooth muscle by inhibition of the enzyme phosphodiesterase and suppresses airway responsiveness to stimuli that cause bronchoconstriction. Molecular Weight. Mechanism of Action. Classifications of bronchodilators include beta 2-agonists, anticholinergics, and xanthine derivatives. Classification: Bronchodilator, Xanthine. Ipratropium Bromide administration. Xanthine derivative 152. A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. 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